News – Page 2 – LUMICKS

Blog posts

Cell avidity-tuning ensures safe CAR-T therapy for solid tumors

Dive into our latest article where we shine the spotlight on the groundbreaking work carried out at the Dana-Farber Cancer Institute at Harvard Medical School where researchers utilized cell avidity-tuning to ensure the safety of their CAR-T therapy for targeting solid tumors.

niels5 June 2024

Blog posts

Chromatin remodeling dynamics revealed at the single-molecule level in a recent pioneering study

Explore groundbreaking research on chromatin remodeling dynamics using the C-Trap, revealing 'hopping' and 'sliding' mechanisms of chromatin remodelers on DNA. Gain insights into the push-pull model and its implications for gene regulation and genomic integrity. Dive into the latest advancements in genomic research.

Chenlu Yu30 May 2024

Press releases

LUMICKS Appoints Hugo de Wit as CEO and Executive Board Director

Life Sciences Veteran Joins To Accelerate Company Growth Amsterdam, the Netherlands – May 29, 2024 – LUMICKS, a leading life science tools company that develops instruments for dynamic single-molecule and cell avidity analysis, today announced that Hugo de Wit has been appointed Chief Executive Officer, based in the Company’s headquarters…

Chenlu Yu29 May 2024

DNA repair pathwya via PARP1-DNA co-condensation

Blog posts

Securing Broken DNA Ends: PARP1’s Vital Role in Co-Condensation with DNA

Explore how PARP1's involvement in DNA repair through condensate formation secures genetic integrity. Read this blog to understand the dynamics of DNA repair processes in real-time.

Chenlu Yu19 March 2024

Blog posts

Unveiling Key Mechanisms in Kinetochore-Mediated Chromosome Segregation with the C-Trap

Dr. David Barford's study unveils kinetochore dynamics using LUMICKS C-Trap, shedding light on chromosome segregation mechanisms

Chenlu Yu30 January 2024

Blog posts

From Handshakes to Hugs: Embracing the Dynamics of Immunological Synapse Strength and Avidity

What is an immune synapse? An immunological (or immune) synapse is the interface between a cancer and an immune cell , which is formed in a highly stable, organized manner. The immunological synapse is composed of all intercellular interactions taking place at the interface between the interacting pair, including TCR clustering, co-receptor binding, cell-cell adhesion…

Adrià Ferragut17 January 2024

Blog posts

Towards safe and precise gene therapies: revealing the impact of DNA Supercoiling on CRISPR-Cas9 specificity

CRISPR-Cas9 represents one of the most impactful discoveries in the field of genetic engineering and medicine of recent times. Its discovery catalyzed a paradigm shift in the treatment approach to many genetic diseases, paving the way to simple and effective gene therapy for a large class of diseases. In fact, the…

Chenlu Yu5 December 2023

Blog posts

Cell mechanics with the C-Trap – cellular tension propagation revisited

Surprising insights into the roles of membranes and the actin cytoskeleton in cellular tension propagation – congratulations to all authors for successfully implementing a new and elegant assay with the C-Trap! There was a long-standing dispute in the scientific community about whether the actin cortex facilitates or impedes tension propagation…

Chenlu Yu28 November 2023

Press releases

Breakthrough Research Published in Nature Enabled by Dynamic Single-Molecule Analysis Reveals Crucial Structure-Function Insights into DNA Repair, Resulting in New Cancer Fighting Strategies

Amsterdam, the Netherlands – July 14th, 2023 – LUMICKS, a cutting-edge life science tools company and the leading supplier of dynamic single-molecule and cell avidity analysis instruments, today announced the publication of ground-breaking cancer research in Nature. The research, enabled by LUMICKS’ C-Trap® dynamic single-molecule analysis technology, reveals new crucial…

j.yeh19 July 2023

Blog posts

The C-Trap uncovers new insights into the mechanisms for ATP-dependent chromatin remodeling

PICH (Plk1-interacting checkpoint helicase) belongs to the SNF2 family of ATP-dependent chromatin remodelers. However, what makes PICH unique is that it lacks a nucleotide-binding domain despite having a great affinity for bare DNA. Because of this molecular structure, it has been hypothesized that the binding of PICH to chromatinized bridges…

Chenlu Yu13 June 2023

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