News – Page 13

Blog posts

LUMICKS in Top 250 Scale-ups 2020 of the Netherlands!

We're proud to be amongst the top 250 fastest growing scale-up companies in the Netherlands! Every year, the Erasmus Centre for Entrepreneurship (ECE) led by Prof. Dr. Justin Jansen, Academic Director of ECE and professor of Corporate Entrepreneurship at Rotterdam School of Management, researches the trends in the Dutch scale-up landscape. The…

j.yeh9 March 2020

Blog posts

A new DNA–protein coupling procedure improves stability for DSM analyses

A recent study in Communications Chemistry shows how a research lab at AMOLF in the Netherlands optimized DNA–protein coupling to study dynamic processes requiring high forces and long-term assessments. Using their C-Trap® Optical Tweezers – Fluorescence Microscopy system, the team showed the superiority of a ligation-based strategy to create long…

j.yeh5 March 2020

Blog posts

Study shows how chaperone enzyme ClpB processively translocates polypeptide loops using C-Trap^® correlated optical tweezers and confocal microscopy

A new study published in Nature reports how researchers verified the intricate process of disaggregating entangled proteins by analyzing chaperone enzyme ClpB at a single-molecule level. The C-Trap® correlated optical tweezers and confocal microscopy enabled them to analyze how the member of the Hsp100 chaperone family translocates looped polypeptide substrates…

j.yeh13 February 2020

Top banner image was licensed by Sergey Novikov / Shutterstock.com

Blog posts

C-Trap^® installed at Technical University of Munich

We are happy to announce the recent installation of the C-Trap® at the Technical University of Munich, Germany, in the lab of Prof. Matthias Rief. The installed C-Trap combines optical tweezers with 2-color fluorescence microscopy and will be used by students and postdocs in the Rief lab. Among other areas,…

j.yeh11 February 2020

Blog posts

Dynamic Single-Molecule Workshops in North and South of China

Last week we organized two dynamic single-molecule workshops in the North and South of China – one at Tsinghua University in Beijing, and another at Sun Yat-sen University (SYSU). Both workshops included in-depth lectures exploring different state-of-the-art single-molecule applications and hands-on demonstrations of the C-Trap® Optical Tweezers – Fluorescence & Label-free Microscopy technologies. With…

j.yeh18 December 2019

Blog posts

C-Trap^® installed at Tel Aviv University

We are happy to announce the recent installation of the C-Trap™ at Tel Aviv University, Israel, in the lab of Dr. Raya Sorkin. The C-Trap combines optical tweezers with confocal microscopy and is now available to students and postdocs in Dr. Sorkin’s lab, as well as several collaborators on…

j.yeh11 December 2019

Blog posts

Single-molecule study assesses how cohesin complexes bridge DNA molecules using C-Trap^® correlated optical tweezers with fluorescence microscopy

In a new study published in the journal Science Advances, Gutierreu-Flux™Escribano et al. studied the role of cohesin complexes in DNA tethering to gain a better understanding of sister chromatid cohesion. Using the C-Trap correlated optical tweezers with fluorescence microscopy, they observed in real-time intermolecular (DNA–DNA) and intramolecular cohesin-derived DNA bridge…

j.yeh5 December 2019

Blog posts

New application note shows how to study processes associated with phase separation in real time using the C-Trap^®

We are excited to tell you that our application note Manipulate and Study Protein Droplet Dynamics and Properties in Real Time to Understand Phase Separation is now available to download. Here, you can learn how to unravel the properties, formation, and nature of protein droplets, associated with both healthy and…

j.yeh28 November 2019

Blog posts

Study finds essential Cas9–DNA interaction downstream of PAM using a single-molecule approach

A new publication shows how the lab of Dr. Bo Sun used the m-Trap® to analyze the interactions between a Cas9–gRNA complex and DNA. Using a single-molecule approach to unzip the target double-stranded DNA, the team showed interaction points on the DNA that affected Cas9 binding and cleavage. These results can…

j.yeh21 November 2019

Top banner image was licensed by The University of Vermont / Flickr.

Blog posts

C-Trap^® installed at University of Vermont

We are happy to announce the recent installation of the C-Trap® at the University of Vermont Larner College of Medicine. Several labs will use the correlated optical tweezers – fluorescence microscopy instrument to investigate the dynamics of molecular machines that interact with their tracks to generate force and motion. These processes are…

j.yeh22 October 2019

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