News – Page 10

Blog posts

Researchers study the viscoelasticity of human cells as a response to external cues using the high-throughput AFS®

A recent publication in Small introduces you to the value of acoustic force spectroscopy (AFS®) to study the viscoelastic properties of individual cells in high throughput. The authors describe how they used this “plug-and-play” instrument to measure mechanical cell properties upon external cues seamlessly. Romanov et al. specifically assessed how alterations to…

j.yeh16 February 2021

Press releases

LUMICKS enters collaboration with LAVA Therapeutics to characterize its tumor-specific γδ T-cell engagers

In their quest of creating safe and effective immunotherapy cancer treatments, LUMICKS and LAVA Therapeutics joined forces. The partnership aims to evaluate the efficacy of various tumor-specific γδ T-cell engagers based on the resulting binding strengths (cell avidity) between T cells and tumors, measured with LUMICKS newly installed z-Movi® Cell…

j.yeh4 December 2020

Blog posts

Distal bridging between nucleosomes by polycomb complex PRC2 identified with the C-Trap^®

A recent study published in PNAS used single-molecule force spectroscopy to examine unknown interaction mechanisms between polycomb repressive complex 2 (PRC2) and chromatin. The authors evaluated arrays of multiple nucleosomes using their C-Trap® optical tweezers system and identified distal nucleosome bridging by PRC2. The findings provide a better understanding of…

j.yeh3 December 2020

Blog posts

C-Trap^® installed at Emory University in Atlanta

We are happy to announce the installation of a new C-Trap® system with correlated optical tweezers and three-color confocal imaging functionality at Emory University in Atlanta, Georgia. The installed instrument, which is managed by the research group of Prof. Laura Finzi and Dr. David Dunlap, will be used by several…

j.yeh18 November 2020

Press releases

LUMICKS enters strategic collaboration with Leucid Bio to evaluate next-generation pCARs

LUMICKS is pleased to announce a collaboration agreement with clinical-stage biotech company Leucid Bio, which seeks to utilize LUMICKS’ z-Movi® Cell Avidity Analyzer to accelerate entry of immunotherapeutic candidates into clinical trials. The goal of the partnership is to evaluate the efficacy of Leucid Bio’s next-generation CAR T-cells using the…

j.yeh30 October 2020

Blog posts

New study highlights interconvertible RecA–ssDNA states with the help of u-Flux™ microfluidics

A recent publication in FEBS Letters describes how the presence of ADP and ATP affects the structural transitions that single-stranded DNA (ssDNA) undergoes upon RecA-filament assembly. The researchers used the u-Flux™ Laminar Flow Microfluidics combined with optical tweezers to demonstrate that the bacterial homologous recombination-enzyme exists in two interconvertible states.…

j.yeh29 October 2020

Blog posts

Force-dependent actin filament-binding by α-catenin recorded with the C-Trap^®

A recent publication in the journal eLife describes a multidisciplinary study evaluating how the mechanical properties of actin filaments regulate the binding of associated proteins. Specifically, the researchers used the C-Trap® to demonstrate how applied forces on actin filaments enhance binding of cell–cell adhesion protein α-catenin, but not its homolog…

j.yeh15 October 2020

Blog posts

C-Trap^® installed at the National Center for Biotechnology in Madrid

We are happy to announce the installation of a C-Trap® Optical Tweezers – Fluorescence and Label-free Microscopy system at the National Center for Biotechnology (CNB), Madrid, managed by the lab of Dr. Fernando Moreno-Herrero. The team will use the C-Trap configured with dual traps and correlated three-color confocal to examine…

j.yeh12 October 2020

Press releases

Introduction of LUMICKS consumables and script-sharing platform to facilitate faster, easier, and more reproducible Dynamic Single-Molecule analysis

In a move to broadly unlock Dynamic Single-Molecule (DSM) analysis, LUMICKS simultaneously launched two major initiatives: a new business line for reagents, biochemistry kits, and services, as well as its Harbor platform for sharing of DSM scripts. These new resources dramatically simplify the experimental workflow and make DSM analysis accessible…

j.yeh2 October 2020

Blog posts

LUMICKS featured in LinkedIn Top Start-ups 2020

LUMICKS reached the 6th position in the list LinkedIn Top Start-ups 2020 in the Netherlands. We're extremely proud to be among the most resilient companies during these changing times. The LinkedIn editors define start-ups as privately held companies, that are no more than seven years old, employ over 50 people, and…

j.yeh22 September 2020

Join our newsletter