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Learn about cell avidity analysis

Get a better understanding of cell avidity, why is it important and relevant to understand the mechanism of action through the latest publications, webinars, application notes and white papers

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Sarah Tettamanti, PhD Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori

Cell Avidity Measurements to Understanding the mechanism of action of a novel dual CAR approach with improved efficacy and safety using Cell Avidity

Webinars Marcela Maus

Dr. Marcela Maus, Associate Professor of Medicine Massachusetts General Hospital, Harvard Medical School

Cell Avidity Measurements to Understand and Enhance CAR-T/Tumor Interactions in Acute Myeloid Leukemia

Dr. Rebecca Larson, PhD Graduate from Harvard University

Cell avidity as a crucial biomarker for CAR T response

Webinars Maria Themeli

Dr. Maria Themeli, Group Leader of Hematology Department at Amsterdam UMC Cancer Center Amsterdam

Enhanced avidity through combining a BCMA CAR and a CD38 chimeric co-stimulatory receptor leads to enhanced T cell sensitivity and persistence

Webinars Mark Lowdell

Prof. Mark Lowdell, Professor of Cell & Tissue Therapy at University College London and Chief Scientific Officer of INmune Bio, Inc

Exploring the network of cellular interactions of Natural Killer cells in the tumor microenvironment with cell avidity

Webinars Carlos Fernandez de Larrea

Prof. Carlos Fernandez de Larrea, Associate Professor of Medicine University of Barcelona

Dual-targeted cell therapy targeting BCMA and GPRCD5 to prevent relapse in multiple myeloma

Webinars Will Singleterry

Dr. Will Singleterry, Director of Business Development at LUMICKS

Unveiling a one-to-one relationship of TCR-dependent T cell function and cellular avidity at single-cell level using acoustic force

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Rapid assessment of CAR T-cell therapy strategies for multiple myeloma with the cell avidity analysis

Prof. Carlos Fernandez de Larrea Associate Professor of Medicine at University of Barcelona

Identify functionally optimal TCR-engineered T cells through cell avidity measurements

Dr. Natalie Rufer Associate Professor at University of Lausanne

Increased cell avidity through CD38 co-receptor drives enhanced BCMA CAR T-cell sensitivity and persistence in multiple myeloma

Dr. Maria Themeli Group Leader of Hematology Department at Amsterdam UMC Cancer Center Amsterdam

Cell avidity measurement: a new accurate method to predict in vivo CAR T cell efficacy and minimize drug discovery timelines

Dr. Marcela Maus Associate Professor at Harvard Medical School and Director of Cellular Immunotherapy at Massachusetts General Hospital

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Unlocking the Power of Memory-Like NK Cells using Cell Avidity: A New Frontier in Cancer Immunotherapy

Natural killer (NK) cell-based immunotherapies have shown promise in cancer treatment, but their clinical efficacy is often limited by poor persistence and reduced functionality, especially post-cryopreservation….

Cell Avidity uncovers critical binding mechanism impairing T-cell potency in the Tumor Microenvironment

Recent advances in T cell-based immunotherapies, such as checkpoint blockade and adoptive cellular therapy, have revolutionized cancer treatment. However, the tumor microenvironment (TME) remains a significant barrier, limiting the effectiveness of these therapies through several…

Cell avidity-tuning ensures safe CAR-T therapy for solid tumors

Next generation chimeric antigen receptor (CAR) T cell therapies holds the promise in providing a curative solution for solid tumors. Nonetheless, the significant clinical hurdle of on-target off-tumor toxicity (OTOT) remains a major impediment…

Cell Avidity screening deployed by T cell pioneers to accelerate the identification of functional TCRs

T cell receptor (TCR) engineered T-cell therapy shows tremendous potential in combating metastatic melanoma, synovial sarcoma and myeloma, as evidenced by numerous ongoing clinical trials….

Learn about our technology

How does the z-Movi technology work?

Introducing the acoustic technology within the heart of our z-Movi

The z-Movi workflow

How to perform cell avidity analsis experiments in a mater of hours

What is immunological synapse?

Learn how the formation of an immune synaptic interface between T cells and tumor cells leads to activities required for T cell activation and cytokine release

What is avidity and why is it important?

Understanding the term “cell avidity” and how it fills the current scientific research gap

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