Blog posts Archives - Page 3 of 7

Blog posts

Two Chinese universities now equipped with a C-Trap^® system

We are very pleased to announce two new C-Trap® installations in China, one at the Microscopy Core Facility at Westlake University and one at the Institute of Advanced Studies at Soochow University. We begin with the group of Dr. Huizhong Xu at the Institute of Advanced Studies, Soochow University. Their…

Ron Eliyahoo15 June 2021

Blog posts

C-Trap^® reveals how HP1α-mediated heterochromatin modulates its stability in response to applied forces

In a recent publication by Keenen et al. in eLife, the authors uncover the biophysical properties of heterochromatin protein 1α (HP1α) and present a new model on how it mediates DNA condensation and phase separation. Employing a combination of ensemble and single-molecule assays, they found that within phase-separated HP1α-DNA condensates,…

Nelli Bossert9 June 2021

Blog posts

LUMICKS z-Movi^® installed at Charité to measure TCR avidity in T cell therapy research

We are excited to announce the installation of a z-Movi® Cell Avidity Analyzer at Charité – Universitätsmedizin Berlin! The z-Movi will be used by the research team led by Dr. Matthias Leisegang, Juniorprofessor at the Institute of Immunology. This unique instrument measures the interaction strength between target tumor cells and effector…

Erica Fong1 June 2021

Blog posts

New insights into the dynamics of initial replisome assembly uncovered by the C-Trap^®

In a recent article published in Nature Communications, Sanchez et al. successfully employed LUMICKS’ C-Trap® to discover new insights into the molecular dynamics of initial replisome formation. In a collaborative effort between Prof. Dekker (TU Delft) and Prof. Diffley (Francis Crick Institute) laboratories, the scientists uncovered that origin recognition complex…

Nelli Bossert18 May 2021

Blog posts

Three C-Trap^® systems installed in the US East Coast

We are excited to share that three more institutes on the US East Coast are now equipped with a C-Trap® Optical Tweezers – Fluorescence Microscope! The three new instruments are now housed at a new core facility at MSKCC, at the NanoSystems Laboratory at the OSU, and at the UPMC-Hillman Cancer…

Doenja Jansen17 May 2021

C-Trap® installed at Imperial College London, UK

Blog posts

LUMICKS DSM technologies installed in South East UK

We are happy to share our news about the most recent C-Trap® and m-Trap® installations in the UK! We’ll start with the recently installed C-Trap system at the MRC-London Institute of Medical Sciences, Imperial College London that is used by the cell biologists and biochemists at the group of Prof. Luis…

Ron Eliyahoo4 May 2021

Blog posts

Highly reproducible single-molecule analysis of transient structures of native proteins using m-Trap^® dual optical tweezers combined with Raman spectroscopy

A recent publication by Dai et al. in Nature Communications presents an optical tweezers-coupled Raman spectroscopy platform providing tuneable and reproducible surface-enhanced Raman spectroscopy (SERS) measurements. By combining a Raman microscope with the dual-trap optical tweezers and microfluidic flow chamber of the m-Trap®, the scientists were able to characterize three…

Nelli Bossert8 April 2021

Blog posts

Measure interaction strength between target cell and TCR T-cell in HPV-related cancers with the z-Movi^®

In a recent review article in Immunology, Fakhr et al. presented the z-Movi® Cell Avidity Analyzer as a solution to characterize T-cell populations by measuring the binding strength between immune and cancer cells using non-invasive acoustic force. Binding events between a T-cell and its target cell determine the initiation of…

Erica Fong26 March 2021

C-Trap® installed at University of Groningen, NL

Blog posts

New C-Trap^® installation at the University of Groningen opens avenues for investigating the conformational cycle of chaperone proteins

We are thrilled to announce the installation of a C-Trap® at the University of Groningen, Netherlands, in the lab of Dr. Katarzyna (Kasia) Tych. The installed C-Trap combines optical tweezers with 3-color fluorescence microscopy, which the team will use to investigate protein stabilities, molecular chaperoning, and conformational regulation. They plan…

Ron Eliyahoo23 March 2021

Blog posts

Recent m-Trap^® installation at the University of Liège will unlock new potential in dynamic folding experiments

We are happy to announce the recent installation of the m-Trap® at the University of Liège, Belgium, in the lab of Prof. Dr. Anne-Sophie Duwez. The installed m-Trap will provide her team with ultra-high force resolution and stability for their research in single-molecule mechanical unfolding experiments and the means to…

Ron Eliyahoo16 March 2021

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Blog posts

Two Chinese universities now equipped with a C-Trap^® system

C-Trap^® reveals how HP1α-mediated heterochromatin modulates its stability in response to applied forces

LUMICKS z-Movi^® installed at Charité to measure TCR avidity in T cell therapy research

New insights into the dynamics of initial replisome assembly uncovered by the C-Trap^®

Three C-Trap^® systems installed in the US East Coast

LUMICKS DSM technologies installed in South East UK

Highly reproducible single-molecule analysis of transient structures of native proteins using m-Trap^® dual optical tweezers combined with Raman spectroscopy

Measure interaction strength between target cell and TCR T-cell in HPV-related cancers with the z-Movi^®

New C-Trap^® installation at the University of Groningen opens avenues for investigating the conformational cycle of chaperone proteins

Recent m-Trap^® installation at the University of Liège will unlock new potential in dynamic folding experiments

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