Cellular Signaling and Function

Part of: Cellular Structure and Transport

Today’s scientific trends are racing towards smaller scales and experimentation that provides both structural and mechanistic insights. To decipher the activity and mechanical properties of cellular components you need methods that combine visualization capabilities with force measurements and manipulation. We offer solutions that enable you to measure, manipulate and visualize individual filaments and their motors in real-time, with both high throughput and resolution.

You can use optical tweezers to trap and move microscopic objects in space using the attractive and repulsive forces exerted by a laser beam. For example, trap a microscopic polystyrene bead and guide it in proximity to a cell, or trap small components within a multicellular organism to study cellular functions and properties. Correlating the optical tweezers with fluorescence and label-free microscopy enables you to visualize every step of the cellular processes while at the same time measuring and manipulating them in real time. Use the optical tweezers – fluorescence and label-free microscopy, to study cell properties in different contexts:

  • Apply external forces to manipulate cell surfaces and follow cellular components simultaneously with multi-color confocal microscopy.
  • Measure forces associated with filopodia formation and track their interactions using fluorescence microscopy.
  • Trap and manipulate small components and organelle structures in multicellular organisms using brightfield microscopy.
  • Control the temperature and finetune the laser intensity to provide relevant physiological and harmless conditions.

Learn more about:
Optical Tweezers and Fluorescence Microscopy
Optical Tweezers and Fluorescence Microscopy


The combination of optical tweezers and fluorescence microscopy allows for simultaneous manipulation and visualization of molecular interactions in real-time.



Optical Tweezers and Fluorescence Microscopy


Optical Tweezers

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