AFS

New study maps internal and external structures of red blood cell aggregates by combining AFS™ and 3D imaging

Researchers used acoustic force spectroscopy (AFS™) in combination with 3D imaging to induce clustering and rotation of red blood cells, enabling them to study the properties of cell aggregates. The new approach, which is based on radiation and stream forces, … Continue Reading

New study evaluates the dynamics behind viral assembly at the single-molecule level using both C-Trap™ and AFS™

Researchers used the C-Trap™ optical tweezers – fluorescence microscopy system and acoustic force spectroscopy (AFS) to study the processes underlying viral assembly. The study evaluated the capsid formation and DNA condensation of virus-like particles (VLPs) at the single-molecule level and … Continue Reading

C-Trap™ & AFS™ installed at Tianjin University

LUMICKS is proud that Tianjin University, China, is now equipped with both a C-Trap™ Optical Tweezers-Fluorescence Microscopy and AFS™ Parallel Single-Molecule Force Spectroscopy. The systems are installed in the State Key Laboratory of Precision Measurement Technology and Instruments. Both systems will contribute to … Read More

Dynamic Single-Molecule Workshops at UC Berkeley and University at Buffalo

In the last couples of weeks, two dynamic single-molecule workshops took place at both sides of the United States – one at the University of California, Berkeley, CA, and another at the University at Buffalo, NY. Both workshops included in-depth … Read More

AFS installation at Gottingen

AFS™ installed at University of Göttingen

An AFS™ system was installed in the lab of Professor Andreas Janshoff at the Department of Biophysical Chemistry at the University of Göttingen, Germany. Together with the team of Professor Claudia Steinem (Institute for Organic and Biomolecular Chemistry), the Janshoff … Continue Reading

First AFS™ installed in Australia

The very first AFS™ Acoustic Force Spectroscopy-system in Australia has been successfully installed in the lab of Prof. Boris Martinac at the Victor Chang Cardiac Research Institute. Prof. Martinac and his team conduct research on cellular transduction processes associated with mechanosensitive ion channels. Although it … Read More

Single-Molecule Workshop at the Bustamante Lab (UC Berkeley)

The series of our successful single-molecule workshops continued on October 30 – November 1 at the Bustamante Lab (University of California, Berkeley). Both days started off with interesting seminars given by researchers from three top single-molecule labs. Dr. Shannon Yan (Bustamante Lab) presented … Read More

Single-Molecule Workshops at the Rockefeller University and LUMICKS Amsterdam

During the end of October, we organized two single-molecule workshops at the Rockefeller University, NY, and our headquarters in Amsterdam. The participants in Amsterdam had the great opportunity to attend an inspiring lecture given by Prof. Mattias Rief (Technical University of Munich), … Read More

Application Note Enzymatic Activity Now Online

Enzymatic Activity and Inhibition Efficiency Application Note Now Online

The characterization of the enzymatic activity of proteins involved in the DNA machinery and the identification of their inhibitors are key for the development of a variety of treatments. It is essential to collect statistically-relevant data, which is typically achieved … Continue Reading

Measure Cell Mechanics with Acoustic Force Spectroscopy

Novel Method for Single-Cell Mechanical Probing using LUMICKS’ AFS™ System

The article ‘Probing cellular mechanics with Acoustic Force Spectroscopy’ has recently been published in the journal Molecular Biology of the Cell. Congratulations to all the authors on their inspiring research! Undergoing deformations plays a vital role in the function of Red … Continue Reading