Super Resolution CTFM in Nature Methods

Super Resolution Correlative Tweezers Fluorescence Microscopy (SR-CTFM) was featured in Nature Methods. The VU team presented the CTFM single-molecule approach capable of visualizing individual DNA-binding proteins on densely covered DNA and in the presence of high protein concentrations. The method combines optical tweezers with multicolour confocal and stimulated emission depletion (STED) fluorescence microscopy. Proteins on DNA are visualized at a resolution of 50 nm, a sixfold resolution improvement over that of confocal microscopy.

View the article here.

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