Skip to main content

General news

Stay up to date on relevant publications, installations, and more

Publications

Explore a range of publications within our dynamic single-molecule application field Buzón, P. et al. The Histone Chaperones SET/TAF‐1β and NPM1 Exhibit Conserved Functionality in Nucleosome Remodeling and Histone Eviction in a Cytochrome c ‐Dependent Manner. Advanced Science (Wouter Roos, University of Groningen) 2023   Fazio, N. et al. E. coli…
j.yeh
4 January 2022

Drug research

How dynamic single-molecule analysis contributes to drug research One of the big challenges in drug discovery today is that all current life science tools working at the molecular level either measure static structure or average binding kinetics; the crucial and often very complex mechanical details of the underlying dynamic process are often not…
j.yeh
4 January 2022

Publications

Read the latest publications from LUMICKS instruments hereWang et al., Affinity fine-tuning anti-CAIX CAR-T cells mitigate on-target off-tumor side effects, Molecular Cancer, 2024Boucher et al., Bispecific CD33/CD123 targeted chimeric antigen receptor T cells for the treatment of acute myeloid leukemia, Molecular Therapy Oncology, 2023Bouti et al., SIGLEC-5/14 Inhibits CD11b/CD18 Integrin Activation…
j.yeh
4 January 2022

The z-Movi workflow

The z-Movi workflow We've optimized the z-Movi workflow to facilitate excellent user experience and provide you with reliable and reproducible results in a matter of minutes. The z-Movi Chip is made to simplify cell culturing and maintain your samples in physiological conditions while you perform experiments. Once you have performed…
Adrià Ferragut
23 November 2021
Acoustic force spectroscopy for cell analysis

How does the z-Movi technology work?

How does it work in practice? It all starts with the Acoustic Force Spectroscopy principle At the heart of the z-Movi technology, inside the microfluidic chip, you will find the piezo element that generates resonant acoustic waves. These ultrasound waves are the foundation of cell avidity analyses, as they can pull cells vertically toward the…
Adrià Ferragut
11 November 2021

IRM (label-free)

What is IRM microscopy? Interference reflection microscopy (IRM) is an optical microscopy technique that takes advantage of polarized light to form an image of an object on a glass surface1-2. The intensity of the signal is a measure of the proximity of the object to the glass surface. This technique…
Adrià Ferragut
16 November 2021

TIRF

What is TIRF microscopy? Total internal reflection fluorescence (TIRF) microscopy excites fluorophores in a thin region of the sample1. Only fluorescent molecules that are close to the solid (usually the surface of a glass coverslip) are efficiently excited. This enables you to visualize surface-bound molecules or cells with high resolution.…
Adrià Ferragut
17 November 2021
Immune synapse cell avidity and cell killing

What is an immunological synapse?

What is an immune synapse and why is it relevant for cell therapy?​ An immunological synapse is an interface between an antigen-presenting cell or a target cell and a lymphocyte or a natural killer cell, which is formed in a highly stable, organized manner. The immunological synapse is composed of all intercellular interactions between the interacting pair, including TCR clustering, checkpoint…
j.yeh
24 February 2021

STED Super Resolution

What is STED nanoscopy? Stimulated emission depletion (STED) is a fluorescence microscopy technique that facilitates visualization of sub-cellular organization with unprecedented detail. Stefan Hell, the person who created STED, got the Nobel Prize in Chemistry in 2014 for this invention. STED can achieve super-resolution, bypassing the diffraction limitations of confocal…
Adrià Ferragut
21 July 2021
Cell avidity: a new biomarker for IO research

What is avidity and why is it important?

Cell Avidity: the missing biomarker in immuno-oncology Binding events between an immune cell and its target tumor cell determine the initiation of immunological synapse formation. This in turn sets a series of important events in motion, such as activation, expansion, tumor cell elimination and persistence. These events are all a function of the signals provided upon that initial binding event. Cell–cell interactions are, therefore,…
j.yeh
19 February 2021
Close Menu

For pricing, reach out to your application scientist or account manager

Open Email

Fill in our contact form, we will reach out to you!

Please include ‘Lakeview data analysis price inquiry’ in the Message box

Contact Us


Join our newsletter

Get exclusive news on the latest publications, product developments, events and breakthrough science.

By submitting the form you agree to LUMICKS' privacy policy. You can revoke your consent at any time.

Download our webinar recording:

 

Download our Cell Therapy (CAR-T, TCR, NK) applications deck