Enzymatic Activity and Inhibition Efficiency Application Note Now Online

Application Note Enzymatic Activity Now Online

The characterization of the enzymatic activity of proteins involved in the DNA machinery and the identification of their inhibitors are key for the development of a variety of treatments. It is essential to collect statistically-relevant data, which is typically achieved by using enzymatic assays designed for high-throughput screening applications. However, while these assays provide valuable insights into the bulk characteristics of enzymes, they suffer from the limitation that the unique behavior of each molecule is averaged out. Acoustic force spectroscopy has the unique ability to measure the activity of hundreds of enzymes in parallel, while retaining valuable information, such as the processivity, rate and pausing steps of each individual enzyme.

The Enzymatic Activity and Inhibition Efficiency application note shows how LUMICKS’ AFS™ system can be employed for the study of DNA transcription and the detection of novel transcription elongation inhibitors.

Download the application note here.

Join our newsletter

Join our newsletter

Get exclusive news on the latest publications, product developments, events and breakthrough science.

By agreeing to receive marketing communications, you subscribe to our newsletter. You can change your mind at any time by clicking the unsubscribe link in any marketing email you receive from us. By submitting the form you agree to LUMICKS' privacy policy.

Download our webinar recording:


Download our Cell Therapy (CAR-T, TCR, NK) applications deck