AFS installation at Victor Chang Cardiac Research Institute, AustraliaUncategorised

First AFS™ installed in Australia

The very first AFS™ Acoustic Force Spectroscopy-system in Australia has been successfully installed in the lab of Prof. Boris Martinac at the Victor Chang Cardiac Research Institute. Prof. Martinac and his team conduct research on cellular transduction processes associated with mechanosensitive ion channels. Although it has been shown that dysfunction of these ion channels contributes…
j.yeh
12 March 2019
Uncategorised

New insights into Cas9 off-target activity

The paper “DNA stretching induces Cas9 off-target binding and cleavage” was just published in Nature Structural and Molecular Biology. Congratulations to all the authors! In this paper, scientists at the MRC London Institute of Medical Sciences and AstraZeneca studied how CRISPR-Cas9 differentiates between on-targets and off-targets. They used the C-Trap®…
j.yeh
8 March 2019
C-Trap m-Trap 2019 Brochure CoversUncategorised

Step into the unresolved with the Surface Assay Toolkit

During BPS19, we introduced the Surface Assay Toolkit! A unique assortment of new features that enable scientists to investigate the cytoskeleton from a whole new dynamic perspective. The Surface Assay Toolkit brings together the C-Trap™ and m-Trap™ optical tweezers with:  Label-free surface imaging using IRM;  Rapid fluorescent imaging in solution using Widefield;  Fluorescence surface imaging using TIRF;  High throughput experimental workflow at the surface. Download the 2019…
j.yeh
7 March 2019
LUMICKS Boston Office OpeningUncategorised

LUMICKS Boston Office Opening

Last Friday we officially opened our own office in Boston! After some serious ribbon cutting, the US team celebrated this milestone with delicious food and champagne. We would like to warmly welcome you to stop by whenever you are in the Boston area. Do you notice the typical Dutch details…
j.yeh
11 February 2019
Blog posts

The Scientist Magazine features z-Movi®;

We couldn't have put the essence of our z-Movi®; in better words than the author of this article in The Scientist: "Just as music pulls some folks to the dance floor while others remain stuck to their chairs, sound can now be used to pull some cells loose from their substrate while other cells…
j.yeh
25 January 2019
z-Movi has been featured in ScienceBlog posts

z-Movi® featured in Science

Our latest product, the z-Movi®;, has been featured in the latest issue of the journal Science! The z-Movi uses acoustic force manipulation to query the interaction strengths of cells with their cognate binding partners. It is based on a lab-on-a-chip assay that allows the assessment of thousands of cell-cell and cell-ligand interactions…
j.yeh
5 December 2018
Department of Biochemistry, University of CambridgePress releases

New Centre of Excellence in Dynamic Single-Molecule Analysis for Accelerated Drug Discovery in collaboration with AstraZeneca and the University of Cambridge

The center will be based around LUMICKS’ C-Trap® optical tweezers–fluorescence microscope, which for the first time enables real-time observation and probing of biomolecular interactions. The approach will be pioneered in several pharmacology and biology assays with the aim of accelerating the discovery of potential new drugs.
j.yeh
27 June 2018
G2 product line launchPress releases

LUMICKS launches new generation of dynamic single-molecule analysis instruments setting new standards for life-science research.

On February 17 we introduced our new generation of the C-Trap® optical tweezers-fluorescence microscope and AFS™ Acoustic Force Spectroscopy system at the 62ndAnnual Meeting of the Biophysical Society in San Francisco. The new generation represents an evolution of LUMICKS’ original instruments, which set the benchmark for high-resolution and high-throughput single-molecule…
j.yeh
16 February 2018

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