The novel method of using acoustics for single molecule manipulation and spectroscopy was published in the January 2015 edition of Nature methods.

Force spectroscopy has become an indispensable tool to unravel the structural and mechanochemical properties of biomolecules. Here we extend the force spectroscopy toolbox with an acoustic manipulation device that can exert forces from subpiconewtons to hundreds of piconewtons on thousands of biomolecules in parallel, with submillisecond response time and inherent stability. This method can be readily integrated in lab-on-a-chip devices, allowing for cost-effective and massively parallel applications.

LUMICKS is already offering a prototype version of its commercial solution for AFS™ to selected opinion-leading customers to test this novel method on unexplored applications.

View the publication here.

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